Donna M. Huryn: search on Z-Library

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1

AIDS-driven nucleoside chemistry.

Huryn, Donna M., Okabe, Masami

Journal:

Chemical Reviews

Year:

1992

Language:

english

File:

PDF, 3.05 MB

english, 1992

2

Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum

Annette N. Chiang, Juan-Carlos Valderramos, Raghavan Balachandran, Raj J. Chovatiya, Brian P. Mead, Corinne Schneider, Samantha L. Bell, Michael G. Klein, Donna M. Huryn, Xiaojiang S. Chen, Billy W. D

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 279 KB

english, 2009

3

Cancer Drug Design and Discovery || Natural Product Chemistry and Cancer Drug Discovery

Huryn, Donna M.

Year:

2014

Language:

english

File:

PDF, 2.46 MB

english, 2014

4

Studies toward the discovery of the next generation of antidepressants. Part 6: Dual 5-HT1A receptor and serotonin transporter affinity within a class of arylpiperazinyl-cyclohexyl indole derivatives

Dahui Zhou, Ping Zhou, Deborah A. Evrard, Kristin Meagher, Michael Webb, Boyd L. Harrison, Donna M. Huryn, Jeannette Golembieski, Geoffrey A. Hornby, Lee E. Schechter, Deborah L. Smith, Terrance H. An

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 347 KB

english, 2008

5

Design, synthesis, and evaluation of inhibitors of cathepsin L: Exploiting a unique thiocarbazate chemotype

Michael C. Myers, Parag P. Shah, Mary Pat Beavers, Andrew D. Napper, Scott L. Diamond, Amos B. Smith III, Donna M. Huryn

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 229 KB

english, 2008

6

Total synthesis of (+)-mikrolin

Amos B. Smith III, Yasushi Yokoyama, Donna M. Huryn, Norma K. Dunlap

Journal:

Tetrahedron Letters

Year:

1987

Language:

english

File:

PDF, 249 KB

english, 1987

7

Structure Property Relationships of Carboxylic Acid Isosteres

Lassalas, Pierrik, Gay, Bryant, Lasfargeas, Caroline, James, Michael J, Tran, Van, Vijayendran, Krishna G, Brunden, Kurt R, Kozlowski, Marisa C, Thomas, Craig J, Smith III, Amos B, Huryn, Donna M., Ba

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.66 MB

english, 2016

8

Women in Medicinal Chemistry Special Issue

Blanco, Maria-Jesus, Huryn, Donna M.

Journal:

ACS Medicinal Chemistry Letters

Year:

2020

Language:

english

File:

PDF, 349 KB

english, 2020

9

Discovery of a novel series of Notch-sparing γ-secretase inhibitors

Anthony Kreft, Boyd Harrison, Suzan Aschmies, Kevin Atchison, David Casebier, Derek C. Cole, George Diamantidis, John Ellingboe, Diane Hauze, Yun Hu, Donna Huryn, Mei Jin, Dennis Kubrak, Peimin Lu, Jo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 199 KB

english, 2008

10

[Annual Reports in Medicinal Chemistry] Annual Reports in Medicinal Chemistry Volume 42 Volume 42 || Chapter 26 The Molecular Libraries Screening Center Network (MLSCN): Identifying Chemical Probes of Biological Systems

Huryn, Donna M.

Year:

2007

Language:

english

File:

PDF, 149 KB

english, 2007

11

p97: An Emerging Target for Cancer, Neurodegenerative Diseases and Viral Infections

Huryn, Donna M., Kornfilt, David J. P., Wipf, Peter

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 2.88 MB

english, 2019

12

Synthesis of E-selectin inhibitors: Use of an aryl-cyclohexyl ether as a disaccharide scaffold

Aijun Liu, Kathleen Dillon, Robert M. Campbell, Don C. Cox, Donna M. Huryn

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 235 KB

english, 1996

13

Identification of Novel Inhibitors of Dietary Lipid Absorption Using Zebrafish

Clifton, Justin D., Lucumi, Edinson, Myers, Michael C., Napper, Andrew, Hama, Kotaro, Farber, Steven A., Smith, Amos B., Huryn, Donna M., Diamond, Scott L., Pack, Michael, Zhou, Wen-Liang

Journal:

Year:

2010

Language:

english

File:

PDF, 5.44 MB

english, 2010

14

Pharmaceutical profiling method for lipophilicity and integrity using liquid chromatography–mass spectrometry

Edward H. Kerns, Li Di, Susan Petusky, Teresa Kleintop, Donna Huryn, Oliver McConnell, Guy Carter

Journal:

Journal of Chromatography B

Year:

2003

Language:

english

File:

PDF, 363 KB

english, 2003

15

Molecular Docking of Cathepsin L Inhibitors in the Binding Site of Papain

Beavers, Mary Pat, Myers, Michael C., Shah, Parag P., Purvis, Jeremy E., Diamond, Scott L., Cooperman, Barry S., Huryn, Donna M., Smith, Amos B.

Journal:

Journal of Chemical Information and Modeling

Year:

2008

Language:

english

File:

PDF, 2.26 MB

english, 2008

16

Anabolism and Mechanism of Action of Ro24-5098, an Isomer of 2′,3′-Dideoxyadenosine (ddA) with Anti-HIV Activity

KARL B. FRANK, EDWARD V. CONNELL, MICHAEL J. HOLMAN, DONNA M. HURYN, BARBARA C. SLUBOSKI, STEVE Y. TAM, LOUIS J. TODARO, MANFRED WEIGELE, DOUGLAS D. RICHMAN, HIROAKI MITSUYA, SAMUEL BRODER, IAIN S. SI

Journal:

Annals of the New York Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 297 KB

english, 1990

17

Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation

Christine M. Wright, Raj J. Chovatiya, Nora E. Jameson, David M. Turner, Guangyu Zhu, Stefan Werner, Donna M. Huryn, James M. Pipas, Billy W. Day, Peter Wipf, Jeffrey L. Brodsky

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 292 KB

english, 2008

18

4-(2-Aminoethoxy)-N-(phenylsulfonyl)indoles as novel 5-HT6 receptor ligands

Ping Zhou, Yinfa Yan, Ronald Bernotas, Boyd L. Harrison, Donna Huryn, Albert J. Robichaud, Guo Ming Zhang, Deborah L. Smith, Lee E. Schechter

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 108 KB

english, 2005

19

Synthesis and Biological Activity of a Focused Library of Mitogen-activated Protein Kinase Phosphatase Inhibitors

David M. Arnold, Caleb Foster, Donna M. Huryn, John S. Lazo, Paul A. Johnston, Peter Wipf

Journal:

Chemical Biology & Drug Design

Year:

2007

Language:

english

File:

PDF, 212 KB

english, 2007

20

Identification of Aminothienopyridazine Inhibitors of Tau Assembly by Quantitative High-Throughput Screening

Crowe, Alex, Huang, Wenwei, Ballatore, Carlo, Johnson, Ronald L., Hogan, Anne-Marie L., Huang, Ruili, Wichterman, Jennifer, McCoy, Joshua, Huryn, Donna, Auld, Douglas S.

Journal:

Year:

2009

Language:

english

File:

PDF, 2.35 MB

english, 2009

21

Contributions of Academic Laboratories to the Discovery and Development of Chemical Biology Tools

Huryn, Donna M., Resnick, Lynn O., Wipf, Peter

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 2.19 MB

english, 2013

22

Identification and Characterization of Small Molecule Antagonists of pRb Inactivation by Viral Oncoproteins

Daniela Fera, David C. Schultz, Santosh Hodawadekar, Melvin Reichman, Preston Scott Donover, Jason Melvin, Scott Troutman, Joseph L. Kissil, Donna M. Huryn, Ronen Marmorstein

Journal:

Chemistry & Biology

Year:

2012

Language:

english

File:

PDF, 1.17 MB

english, 2012

23

P4-244

Harrison, Boyd L., Kreft, Anthony, Aschmies, Susan, Atchison, Kevin, Cole, Derek, Ellingboe, John, Hauze, Diane, Hu, Yun, Huryn, Donna, Jin, Mei, Kubrak, Dennis, Lu, Peimin, Mann, Charles, Martone, Ro

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 92 KB

english, 2006

24

Our Scope Expansion to Include Biologics

Maryanoff, Bruce E., Huryn, Donna M.

Journal:

ACS Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 121 KB

english, 2015

25

Women in Medicinal Chemistry Special Issue

Blanco, Maria-Jesus, Huryn, Donna M.

Journal:

ACS Medicinal Chemistry Letters

Year:

2019

Language:

english

File:

PDF, 241 KB

english, 2019

26

Appointments

Harrison, Boyd L., Kreft, Anthony, Aschmies, Susan, Atchison, Kevin, Cole, Derek, Ellingboe, John, Hauze, Diane, Hu, Yun, Huryn, Donna, Jin, Mei, Kubrak, Dennis, Lu, Peimin, Mann, Charles, Martone, Ro

Journal:

Year:

1941

Language:

english

File:

PDF, 236 KB

english, 1941

27

Editorial [Hot topic: Medicinal Chemistry in the Pilot Phase of the Molecular Libraries Screening Center Network (Guest Editor: Donna M. Huryn)]

Journal:

Current Topics in Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 15 KB

english, 2009

28

Women in Medicinal Chemistry Special Issue

Blanco, Maria-Jesus, Huryn, Donna M.

Journal:

ACS Medicinal Chemistry Letters

Year:

2019

File:

PDF, 241 KB

2019

29

A Different Kind of Medicinal Chemistry Toolbox

Huryn, Donna M., Bolognesi, Maria Laura

Journal:

ACS Medicinal Chemistry Letters

Year:

2020

Language:

english

File:

PDF, 967 KB

english, 2020

30

2-Guanidinoquinazolines as new inhibitors of the STAT3 pathway

LaPorte, Matthew G., da Paz Lima, Dimas José, Zhang, Feng, Sen, Malabika, Grandis, Jennifer R., Camarco, Daniel, Hua, Yun, Johnston, Paul A., Lazo, John S., Resnick, Lynn O., Wipf, Peter, Huryn, Donna

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 1.43 MB

english, 2014

31

High-throughput identification of post-transcriptional utrophin up-regulators for Duchenne muscle dystrophy (DMD) therapy

Loro, Emanuele, Sengupta, Kasturi, Bogdanovich, Sasha, Whig, Kanupriya, Schultz, David C., Huryn, Donna M., Khurana, Tejvir S.

Journal:

Scientific Reports

Year:

2020

File:

PDF, 3.75 MB

2020

32

Total synthesis of (-)-gilmicolin

Smith, Amos B., Huryn, Donna M.

Journal:

Journal of Organic Chemistry

Year:

1985

Language:

english

File:

PDF, 378 KB

english, 1985

33

A Case Study from the Chemistry Core of the Pittsburgh Molecular Library Screening Center: The Polo-like Kinase Polo-Box Domain (Plk1- PBD)

Wipf, Peter, Arnold, David, Carter, Karen, Dong, Shuzhi, Johnston, Paul, Sharlow, Elizabeth, Lazo, John, Huryn, Donna

Journal:

Current Topics in Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 324 KB

english, 2009

34

Synthesis of the 6′-Fluoro Derivatives of Carbocyclic 2′,3′-Dideoxy-3′-oxa-adenosine

Tam, Steve, Holman, Michael, Huryn, Donna, Cislo, Andrew

Journal:

Nucleosides and Nucleotides

Year:

1991

Language:

english

File:

PDF, 188 KB

english, 1991

35

Screening of 5-HT 1A Receptor Antagonists using Molecularly Imprinted Polymers

O'Connor, Naphtali A., Paisner, David A., Huryn, Donna, Shea, Kenneth J.

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 5.21 MB

english, 2007

36

PTPRT epigenetic silencing defines lung cancer with STAT3 activation and can direct STAT3 targeted therapies

Sen, Malabika, Kindsfather, Audrey, Danilova, Ludmila, Zhang, Feng, Colombo, Raffaele, LaPorte, Matthew G., Kurland, Brenda F., Huryn, Donna M., Wipf, Peter, Herman, James G.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.58 MB

english, 2019

37

Synthesis and structure–activity relationship of a novel series of heterocyclic sulfonamide γ-secretase inhibitors

Jun Pu, Anthony F. Kreft, Suzan H. Aschmies, Kevin P. Atchison, Joshua Berkowitz, Thomas J. Caggiano, Micheal Chlenov, George Diamantidis, Boyd L. Harrison, Yun Hu, Donna Huryn, J. Steven Jacobsen, Me

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 413 KB

english, 2009

38

Author Correction: High-throughput identification of post-transcriptional utrophin up-regulators for Duchenne muscle dystrophy (DMD) therapy

Loro, Emanuele, Sengupta, Kasturi, Bogdanovich, Sasha, Whig, Kanupriya, Schultz, David C., Huryn, Donna M., Khurana, Tejvir S.

Journal:

Scientific Reports

Year:

2020

Language:

english

File:

PDF, 619 KB

english, 2020

39

Special Issue on Epigenetics: Targeting Chromatin- and RNA- Modifications

Copeland, Robert A., Huryn, Donna M.

Journal:

ACS Medicinal Chemistry Letters

Year:

2020

File:

PDF, 525 KB

2020

40

Synthesis, characterization and evaluation of pro-drugs of VLA-4 antagonists

Donna M Huryn, Susan Ashwell, Reinhardt Baudy, Darren B Dressen, William Gallaway, Francine S Grant, Andrei Konradi, Robert W Ley, Susan Petusky, Michael A Pleiss, Dimitri Sarantakis, Christopher M Se

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 152 KB

english, 2004

41

Design, Synthesis and Biological Evaluation of a Library of Thiocarbazates and Their Activity as Cysteine Protease Inhibitors

Liu, Zhuqing, C. Myers, Michael, P. Shah, Parag, Pat Beavers, Mary, A. Benedetti, Phillip, L. Diamond, Scott, B. Smith,III, Amos, M. Huryn, Donna

Journal:

Combinatorial Chemistry & High Throughput Screening

Year:

2010

Language:

english

File:

PDF, 457 KB

english, 2010

42

Paclitaxel C-10 carbamates: Potential candidates for the treatment of neurodegenerative tauopathies

Carlo Ballatore, Edward Hyde, Robert F. Deiches, Virginia M.-Y. Lee, John Q. Trojanowski, Donna Huryn, Amos B. Smith III

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 200 KB

english, 2007

43

Cyclopentane-1,3-dione: A Novel Isostere for the Carboxylic Acid Functional Group. Application to the Design of Potent Thromboxane (A2) Receptor Antagonists

Ballatore, Carlo, Soper, James H., Piscitelli, Francesco, James, Michael, Huang, Longchuan, Atasoylu, Onur, Huryn, Donna M., Trojanowski, John Q., Lee, Virginia M.-Y., Brunden, Kurt R., Smith, Amos B.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 3.38 MB

english, 2011

44

Molecular Docking of Cathepsin L Inhibitors in the Binding Site of Papain

Beavers, Mary Pat, Myers, Michael C., Shah, Parag P., Purvis, Jeremy E., Diamond, Scott L., Cooperman, Barry S., Huryn, Donna M., Smith, Amos B.

Journal:

Journal of Chemical Information and Modeling

Year:

2010

File:

PDF, 18 KB

2010

45

Identification and synthesis of a unique thiocarbazate cathepsin L inhibitor

Michael C. Myers, Parag P. Shah, Scott L. Diamond, Donna M. Huryn, Amos B. Smith III

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 148 KB

english, 2008

46

Cancer Drug Design and Discovery Volume 83 || Natural product chemistry and anticancer drug discovery

Huryn, Donna M.

Year:

2008

Language:

english

File:

PDF, 510 KB

english, 2008

47

HCS Campaign to Identify Selective Inhibitors of IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines

Johnston, Paul A., Sen, Malabika, Hua, Yun, Camarco, Daniel P., Shun, Tong Ying, Lazo, John S., Wilson, Gabriela Mustata, Resnick, Lynn O., LaPorte, Matthew G., Wipf, Peter, Huryn, Donna M., Grandis,

Journal:

Assay and Drug Development Technologies

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

48

Microtubule-stabilising drugs for therapy of Alzheimer’s disease and other neurodegenerative disorders with axonal transport impairments

Trojanowski, John Q, Smith, Amos B, Huryn, Donna, Lee, Virginia M-Y

Journal:

Expert Opinion on Pharmacotherapy

Year:

2005

Language:

english

File:

PDF, 66 KB

english, 2005

49

A Focused Library of Tetrahydropyrimidinone Amides via a Tandem Biginelli-Ugi Multi-Component Process

Werner, Stefan, Turner, David, Lyon, Michael, Huryn, Donna, Wipf, Peter

Journal:

Year:

2006

Language:

english

File:

PDF, 79 KB

english, 2006

50

Toxicity, pharmacokinetics and metabolism of a novel inhibitor of IL-6-induced STAT3 activation

Kiesel, Brian F., Parise, Robert A., Guo, Jianxia, Huryn, Donna M., Johnston, Paul A., Colombo, Raffaele, Sen, Malabika, Grandis, Jennifer R., Beumer, Jan H., Eiseman, Julie L.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 610 KB

english, 2016

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